ENTRE-OS-RIOS. Entre-os-Rios translates to “between the rivers,” and this small village is, quite appropriately, located at the confluence of the Tâmega and Douro rivers. This tranquil village offers an authentic slice of Douro River life. In the afternoon, indulge in a traditional Portuguese lunch with your fellow travelers in Entre-os-Rios at a local quinta – a country estate – for a truly authentic culinary experience. (B,L,D)

RÉGUA – PINHÃO. Visit the Baroque-style Palacio de Mateus and its gardens. Inside the house, you’ll see interesting furnishings, paintings and a ceiling of intricately carved wood. The gardens here are considered some of the most beautiful in Portugal. Later in the day, savor the flavors of Portugal’s renowned fortified wine, vinho do porto, made exclusively in the Douro Valley. Head to a local quinta for your authentic Port-wine tasting experience and enjoy the sweet nectar of this fascinating region. (B,L,D)

VEGA DE TERRÓN, SPAIN – SALAMANCA. Drive to Salamanca, a UNESCO World Heritage Site. Built of golden sandstone, Salamanca is known as a “living museum,” and you will have an opportunity to step back in time to the Middle Ages during your escorted tour, which includes the city’s elegant university buildings, the New Cathedral, the intriguingly decorated House of Shells and Plaza Mayor. (B,L,D)

BARCA D’ALVA. Spend time soaking up the beauty of the Douro River as you cruise to Barca d’Alva, where you will visit Castelo Rodrigo, a small fortified village perched high on a hilltop with centuries-old walls, steep narrow streets and fantastic views. You can also opt to hike up to the village should you wish a more active exploration. While here, taste some delicious locally grown produce. Be treated to an exclusive dinner at Quinta da Avessada, where you’ll enjoy an authentic and traditional dining experience complete with entertainment. Quinta da Avessada is also a fascinating interactive museum commemorating the history and culture of wine in the Alto Douro region, so you’ll have fun discovering all the various stages of wine production as well as doing plenty of tasting. (B,L,D)

RÉGUA. Travel to picturesque Lamego, home to one of the most important pilgrimage sites in all of Portugal, where you’ll go to the Nossa Senhora dos Remédios (Sanctuary of Our Lady of Remedies). The shrine features a staircase of nearly 700 steps, beautifully decorated with white and blue tiles, which the more active adventurer will want to climb on a guided hike. Concluding both tours, you will have the opportunity to sample local traditional specialties, such as bôlas de Lamego, bread filled with smoked ham; presunto, a type of dry-cured ham; and Espumante, a Portuguese sparkling wine. (B,L,D)

Lively, commercial Oporto is the second largest city in Portugal after Lisbon. Also called Porto for short, the word easily brings to mind the city's most famous product - port wine. Oporto's strategic location on the north bank of the Douro River has accounted for the town's importance since ancient times. The Romans built a fort here where their trading route crossed the Douro, and the Moors brought their own culture to the area. Oporto profited from provisioning crusaders en route to the Holy Land and enjoyed the riches from Portuguese maritime discoveries during the 15th and 16th centuries. Later, port wine trade with Britain compensated for the loss of the spice trade and the end of gold and gem shipments from Brazil. In the 19th century, the city went through a period of new prosperity with the rise of industries. In its wake followed the building of workers' quarters and opulent residences. Since the declaration of Oporto as a World Heritage Site by UNESCO, the city aims to build up a cultural reference that will provide it with a new image, based on deep historical roots. Among the attractions that make Oporto such an interesting place are its graceful bridges spanning the Douro River, a picturesque riverfront quarter and, most notable, its world-famous port wine lodges. Although Oporto is a bustling centre and home to many different businesses, the source of its greatest fame is the rich, sweet fortified red wine we know as port.

Lively, commercial Oporto is the second largest city in Portugal after Lisbon. Also called Porto for short, the word easily brings to mind the city's most famous product - port wine. Oporto's strategic location on the north bank of the Douro River has accounted for the town's importance since ancient times. The Romans built a fort here where their trading route crossed the Douro, and the Moors brought their own culture to the area. Oporto profited from provisioning crusaders en route to the Holy Land and enjoyed the riches from Portuguese maritime discoveries during the 15th and 16th centuries. Later, port wine trade with Britain compensated for the loss of the spice trade and the end of gold and gem shipments from Brazil. In the 19th century, the city went through a period of new prosperity with the rise of industries. In its wake followed the building of workers' quarters and opulent residences. Since the declaration of Oporto as a World Heritage Site by UNESCO, the city aims to build up a cultural reference that will provide it with a new image, based on deep historical roots. Among the attractions that make Oporto such an interesting place are its graceful bridges spanning the Douro River, a picturesque riverfront quarter and, most notable, its world-famous port wine lodges. Although Oporto is a bustling centre and home to many different businesses, the source of its greatest fame is the rich, sweet fortified red wine we know as port.